1. Heart Failure (Acute and Chronic)
📄Definition
Heart failure is a clinical syndrome where the heart is unable to pump sufficient blood to meet the body’s demands.
Types:
HFrEF – Reduced EF (≤40%)
HFpEF – Preserved EF (≥50%)
HFmrEF – Mid-range EF (41–49%)
Acute HF – Sudden decompensation
Chronic HF – Persistent condition
HARD FAIL
HFrEF / HFpEF
Acute vs Chronic
Remodelling
Dyspnoea, fatigue
Fluid overload
Anxiety
Impaired exercise
Low perfusion
Pathophysiology
↓ Cardiac output → ↑ RAAS & SNS → fluid retention, vasoconstriction, remodelling
HFrEF = systolic failure
HFpEF = diastolic dysfunction
Risk Factors
Mnemonic: DAMN HEART
-
Diabetes
-
Age
-
Myocardial infarction
-
NSAIDs/nephrotoxins
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Hypertension
-
Ethanol
-
Arrhythmias
-
Renal dysfunction
-
Thyroid disease
Clinical Features
🧠 Mnemonic: SOB-FACE
SOB (orthopnoea, PND)
Oedema
Breathlessness on lying
Fatigue
Ankle swelling
Cough (nocturnal)
Elevated JVP
📊 Diagnosis
Mnemonic: BE CALMED
BNP or NT-proBNP
Echo (EF + structure)
CXR (pulmonary oedema)
Anaemia check (FBC)
LFTs/U&Es
MI (Troponin)
ECG
Diabetes (glucose/HbA1c)
Other tests: TSH, lipids
CXR FINDINGS
Mnemonic: ABCDE
Alveolar oedema (bat-wing)
Basal effusions
Cardiomegaly
Dilated upper lobe veins
Effusions (interlobar)
Severity – NYHA Classification
Class | Description |
---|---|
I | No limitation |
II | Mild limitation |
III | Marked limitation |
IV | Symptoms at rest |
Chronic Management
Mnemonic: ABCD TENS
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ACEi/ARB/ARNI (e.g. sacubitril-valsartan)
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Beta-blockers (e.g. bisoprolol)
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Controlled diuretics
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Dapagliflozin (SGLT2i)
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Thromboprophylaxis if AF
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Education (diet/weight)
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Non-pharm (rehab, vaccines)
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Spironolactone (MRA)
Acute Decompensated HF Management
Mnemonic: PUMP FAILURE
Position upright
Unload with diuretics
Morphine (rare)
Pressors if hypotensive
Furosemide IV
ACEi withheld if AKI
Investigate cause
Low-flow O2
Ultrasound lungs
Refer to HF team
Echo urgent
🩺 Monitoring
Weight (target: <2kg/week loss)
Monitor U&Es on ACEi/MRA
Echo every 1–2 years
Digoxin monitoring if used
Annual flu + 1-off pneumococcal vaccine
Complications
🧠 Mnemonic: CHAD
Cardiogenic shock
Hypokalaemia / hyponatraemia
Arrhythmias
Death (sudden cardiac)
Differentials
🧠 Mnemonic: LUNG CHAMP
Lung disease (e.g. COPD)
Uraemia
Nephrotic syndrome
GORD
Constrictive pericarditis
Heart valve disease
Anaemia
MI
PE
Last updated in line with NICE NG106 (Chronic heart failure in adults)
Published: September 2018 • Last updated: March 2023
Last reviewed: July 2025
PASSMAP ensures all content is NICE-aligned and reviewed for Physician Associate Registration Assessment (PARA) success.